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信息内容：■产品名称：B淋巴细胞诱导成熟蛋白1抗体/Anti-PRDM1■货号：hy036466■抗体来源：兔■交叉反应：人、大鼠、小鼠、猪、鸡、牛、
信息内容：【产品名称】：口腔癌高表达的蛋白1抗体/Anti-ORAV1【货号】：hy036559【性状】：Lyophilized or Liquid【产品保存】：Store at
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信息内容：gi24血小板受体，也被称为sisp1或pp2135，是一个311个氨基酸的单通I型膜蛋白，含有一个Ig（免疫球蛋白）域。gi24被认为有助于胶原基质浸润生长的基因映射到人类染色体10q22.1编码。10号染色体包含超过800个基因，1亿3500万个核苷酸，包括近4.5%的人类基因组。PTEN基因是重要的抑癌基因位于10号染色体上，当有缺陷，导致遗传
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Role of glutamine deamidation in neurodegenerative diseases associated with triplet repeat expansionsA HypothesisQurratulain HasanRavindra Varma AlluriPragna RaoYog Raj AhujaOriginal ArticleDOI:
10.1385/JMN:29:3Cite this article as: Hasan, Q., Varma Alluri, R., Rao, P. et al. J Mol Neurosci (. doi:10.1385/JMN:29:3
The pathological expansion of unstable trinucleotide repeats is known to cause neurodegenerative diseases. Trinucleotide repeat expansions might prove to be pathological through a variety of mechanisms, including alteration of DNA structure, transcription, RNA-protein interaction, and altered protein conformations/inter-actions. Deamidation of human proteins have been shown to regulate some time-dependent biological processes such as development and aging. In this paper we hypothesize the possible role of glutamine deamidation as a signaling event in the pathogenesis of neurodegenerative diseases associated with triplet repeat expansion.Neurodegenerative diseasestriplet repeat expansiondeamidation and protein functionpolyglutamine diseasesAdachi H., Kume A., Li M., et al. (2001) Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death. Hum. Mol. Genet.
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