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扫码下载糗事百科app4-Hydroxybenzyl Alcohol
分子量124.14
Beilstein号
EC号 210-768-0
MDL号 MFCD
组合的产品项目
上海(1)北方(预计3-5个工作日)
上海(1)北方(预计3-5个工作日)
上海(3)北方(>10)
添加到购物车
114-122°C
储存温度2-8°C
4-羟基苯甲醇;对羟基苄醇;4-羟基苄醇;4-Methylolphenol
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风险声明 (欧洲)
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危害码（欧洲）
个人防护设备
dust mask type N95 (US),Eyeshields,Gloves
Convenient QSAR model for predicting the complexation of structurally diverse compounds with @b-cyclodextrins
Alfonso A Pérez-Garrido, Aliuska A Morales Helguera, Adela A Abellán Guillén, M Natália D S MN Cordeiro, Amalio A Garrido Escudero
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with @b-cyclodextrins (@b-CDs). Several different theoretical...
Inhibition of GABA shunt enzymes&#039; activity by 4-hydroxybenzaldehyde derivatives
Yun-Hai YH Tao, Zheng Z Yuan, Xiao-Qiao XQ Tang, Hui-Bi HB Xu, Xiang-Liang XL Yang
Possible mechanism of the inhibition of GABA-T by HBA and HBM....
Purification and characterization of active-site components of the putative p-cresol methylhydroxylase membrane complex from Geobacter metallireducens.
J?rg Johannes, Alexander Bluschke, Nico Jehmlich, Martin von Bergen, Matthias Boll
p-Cresol methylhydroxylases (PCMH) from aerobic and facultatively anaerobic bacteria are soluble, periplasmic flavocytochromes that catalyze the first step in biological p-cresol degradation, the hydr...
A cascade biodegradable polymer based on alternating cyclization and elimination reactions.
Matthew A MA Dewit, Elizabeth R ER Gillies
Polymers that depolymerize by a cascade of intramolecular reactions in response to the removal of a stabilizing end-cap can allow for an unprecedented degree of control over the polymer degradation pr...
4-Hydroxybenzyl alcohol: A novel inhibitor of tumor angiogenesis and growth.
Matthias W Laschke, Antonia E Vorsterman van Oijen, Christina K?rbel, Claudia Scheuer, Michael D Menger
The herbal compound 4-hydroxybenzyl alcohol (HBA) is a pleiotropic agent, which has been shown to effectively inhibit the development of new blood vessels by targeting multiple mechanisms of the angio...
In vitro and in vivo evaluation of the anti-angiogenic actions of 4-hydroxybenzyl alcohol.
M W Laschke, A E Vorsterman van Oijen, C Scheuer, M D Menger
4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actio...
p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia.
Kyung-Yoon KY Kam, Seong Jin SJ Yu, Nahee N Jeong, Jeong Hwa JH Hong, Angela M A Anthony AM Jalin, Sungja S Lee, Yong Won YW Choi, Chae Kwan CK Lee, Sung Goo SG Kang
The therapeutic goal in treating cerebral ischemia is to reduce the extent of brain injury and thus minimize neurological impairment. We examined the effects of p-hydroxybenzyl alcohol (HBA), an activ...
Reduction of oxidative stress by p-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant
Soojin S Kim, Hyunjin H Park, Yiseul Y Song, Donghyun D Hong, Onyou O Kim, Eunhye E Jo, Gilson G Khang, Dongwon D Lee
The large production of reactive oxygen species (ROS) leads to the oxidative stress and the subsequent functional decline of organ systems. p-Hydroxybenzyl alcohol (HBA) is known to play a pivotal pro...
4-hydroxybenzyl alcohol ameliorates cerebral injury in rats by antioxidant action.
Shan-Shan SS Yu, Jing J Zhao, Shi-Peng SP Lei, Xue-Mei XM Lin, Ling-Li LL Wang, Yong Y Zhao
4-hydroxybenzyl alcohol (4-HBA), one of the phenolic constituents found in many herbal medicinal plants, exhibits beneficial effects in neurological disorders. In the present study, we evaluated 4-HBA...
Antioxidant and anti-inflammatory activities of hydroxybenzyl alcohol releasing biodegradable polyoxalate nanoparticles.
Hyunjin H Park, Soojin S Kim, Sujin S Kim, Yiseul Y Song, Kyungryul K Seung, Donghyun D Hong, Gilson G Khang, Dongwon D Lee
p-Hydroxybenzyl alcohol (HBA) is one of phenolic compounds in herbal agents and plays a pivotal role in protection against oxidative damage-related diseases due to anti-inflammatory effects. We have d...
Supercritical fluid chromatography of myrosinase reaction products in ground yellow mustard seed oil.
Niloufar Choubdar, Shuliu Li, Richard A Holley
Escherichia coli O157:H7 can survive the dry fermented sausage manufacturing process. Compounds generated by enzymatic hydrolysis of glucosinolates present in ground mustard have shown potential antib...
Secondary metabolites of the phytopathogen Peronophythora litchii.
Haihui H Xie, Yaoguang Y Liang, Jinghua J Xue, Qiaolin Q Xu, Yueming Y Jiang, Xiaoyi X Wei
Two new metabolites, 4R*-hydroxy-3,5R*-dimethoxycyclohex-2-enone (1) and 2-hydroxy-N-(2-hydroxyphenyl)propionamide (2), were isolated from solid cultures of the phytopathogen Peronophythora litchii, a...
Neuroprotective effect of 4-hydroxybenzyl alcohol against transient focal cerebral ischemia via anti-apoptosis in rats.
Shan-Shan Yu, Jing Zhao, Wei-Ping Zheng, Yong Zhao
4-hydroxybenzyl alcohol (4-HBA), one of the major active phenolic constituents of Gastrodia elata Blume, a very important traditional Chinese medicinal herb, has been shown to be an effective agent ag...
Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin
Elodie Descamps, Maud Petrault-Laprais, Pierre Maurois, Nicole Pages, Pierre Bac, R??gis Bordet, Joseph Vamecq
Induction of protein disulfide isomerase (PDI) is validated as a main mechanism by which 4-hydroxybenzyl alcohol (4-HBA), an active principle of Gastrodia elata Blume, reduces cerebral infarct volumes...
Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS
Lei-Chwen LC Lin, Yen-Fei YF Chen, Wen-Chuan WC Lee, Yu-Tse YT Wu, Tung-Hu TH Tsai
Gastrodin is a pharmacologically active substance isolated from Gastrodia elata Blume with sedation, anti-convulsion and anti-epilepsy activities. A rapid and sensitive liquid chromatography technique...
Biotransformation and pharmacokinetics of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-beta-D-glucopyranoside, an antioxidant isolated from Origanum vulgare.
Shiuan-Pey SP Lin, Shang-Yuan SY Tsai, Yun-Lian YL Lin, Sheng-Chu SC Kuo, Yu-Chi YC Hou, Pei-Dawn Lee PD Chao
4-(3,4-Dihydroxybenzoyloxymethyl)phenyl- O-beta-D-glucopyranoside (OV-16) is a polyphenolic glycoside isolated from oregano (Origanum vulgare L.), which is a popular Chinese herb and a common spice in...
Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration.
Zheng Cai, Shixiang Hou, Yuanbo Li, Binbin Zhao, Zhaoxiang Yang, Shuguang Xu, Junxue Pu
Both borneol and gastrodin are bioactive substances derived from traditional Chinese medicine. In this paper, the effect of borneol on the distribution of gastrodin to the brain in mice via oral admin...
Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia
Hyeon Ju Kim, In Koo Hwang, Moo Ho Won
Mongolian gerbils subjected to transient global ischemia exhibit neuroprotection against ischemic neuronal cell death in the hippocampal CA1 region when treated with vanillin, 4-hydroxybenzyl aldehyde...
Anti-angiogenic, anti-inflammatory and anti-nociceptive activity of 4-hydroxybenzyl alcohol.
Eun-Ju EJ Lim, Hyun-Jung HJ Kang, Hyun-Joo HJ Jung, Eun-Hee EH Park
4-Hydroxybenzyl alcohol (HBA), one of the well-known phenolic compounds in diverse plants, displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis assay. HBA was sh...
[Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS].
Wei W Zhang, Yu-xin YX Sheng, Jin-lan JL Zhang, Jin-tang JT Xu, Su-qin SQ Sun
The chromatographic fingerprint of Gastrodia elata Bl. (Tianma) was developed to compare the quality of Tianma samples from different habitats and processing methods. The above analysis method was est...
Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis.
Szu-Hsiu SH Liu, I-Horng IH Pan, I-Ming IM Chu
Tyrosinase is a key enzyme catalyzing the rate-limiting step for the biosynthesis pathway of melanin pigment, which is the most important determinant of the color of skin. Inhibiting tyrosinase and re...
Modulation of LPS-stimulated neuroinflammation in BV-2 microglia by Gastrodia elata: 4-hydroxybenzyl alcohol is the bioactive candidate.
Byung-Wook BW Kim, Sushruta S Koppula, Jae-Won JW Kim, Hyung-Woo HW Lim, Jin-Woo JW Hwang, In-Su IS Kim, Pyo-Jam PJ Park, Dong-Kug DK Choi
Gastrodia elata Blume (Orchidaceae, GE) a traditional plant in Oriental countries is known for its enormous benefits to treat headaches, dizziness, vertigo and convulsive illnesses. In the present stu...
Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit.
The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, w...
Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method
W Zhang, Y X Sheng, J L Zhang
In this report, a high-performance liquid chromatography-electrospray ionization mass spectrometric (HPLC-MS) method was used to determine gastrodin (GAS) and p-hydroxybenzylalcohol (HBA) in rat plasm...
The photo-Favorskii reaction of p-hydroxyphenacyl compounds is initiated by water-assisted, adiabatic extrusion of a triplet biradical.
Richard S Givens, Dominik Heger, Bruno Hellrung, Yavor Kamdzhilov, Marek Mac, Peter G Conrad, Elizabeth Cope, Jong I Lee, Julio F Mata-Segreda, Richard L Schowen, Jakob Wirz
We're sorry this abstract is currently not available....
[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium].
Jia-Shun JS Gong, Wei-Peng WP Ma, Jun-Xue JX Pu, Shu-Guan SG Xu, Shuang-Qing SQ Zheng, Chun-Jie CJ Xiao
To investigate the production of p-hydroxymethylphenol-beta-D-glucoside (gastrodin) through biotransformation by plant cell suspension cultures....
Gusanlungionosides A-D, potential tyrosinase inhibitors from Arcangelisia gusanlung.
Ling-Ling LL Yu, Wei-Cheng WC Hu, Gang G Ding, Rong-Tao RT Li, Jian-He JH Wei, Zhong-Mei ZM Zou, Myeong-Hyeon MH Wang
Four new megastigmane glycosides, named gusanlungionosides A-D (1-4), together with 10 known compounds (5-14), were isolated from the stems of Arcangelisia gusanlung. The structures and absolute confi...
Synthesis and biological evaluation of 12 allenic aromatic ethers
San-Yong SY Wang, Wei-Wei WW Mao, Zhi-Gang ZG She, Chun-Rong CR Li, Ding-Qiao DQ Yang, Yong-Cheng YC Lin, Li-Wu LW Fu
Twelve allenic aromatic ethers (2 and 3), some of them are natural products isolated from the mangrove fungus Xylaria sp. 2508 in the South China Sea, were synthesized. Their antitumor activities agai...
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