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Technical Report: Tests and criteria for fire protection of cable penetrations
Tests and criteria for fire protection of cable penetrations
This report is concerned with the test method and criteria used to evaluate the fire resistance of cable penetrations which are installed in fire resistive building elements (e.g., walls and floor/ceiling assemblies). The fire resistance of cable penetrations used in nuclear power generation facilities in the United States are of primary interest here, although this discussion also applies to less critical installations. This report describes three experiments designed to assess the effects of furnace pressure and excess pyrolyzates on the post-flashover fire performance of barrier assemblies that contain cable penetrations. The effects of the parameters are evaluated for penetrations that have a range of fire resistance. It will be shown that the fire resistance of penetrations is primarily dependent upon the pressure difference between the test furnance and the unexposed face of the penetration and, to a lesser degree, on the presence or absence of excess pyrolyzates.
Publication Date:
OSTI Identifier:6671714
Report Number(s):NUREG/CR-2377; SAND-81-7160 ON: DE
DOE Contract Number:AC04-76DP00789
Resource Type:Technical Report
Resource Relation:Other Information: M illegibility does not permit PC reproduction
Research Org:Lawrence Berkeley Lab., CA (USA)
Country of Publication:United States
Language:English
21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS; BWR TYPE REACTORS; ELECTRIC CABLES; FIRE RESISTANCE; NUCLEAR POWER PLANTS; PWR TYPE REACTORS; FIRE PREVENTION; FIRES; PERFORMANCE TESTING; CABLES; CONDUCTOR DEVICES; ELECTRICAL EQUIPMENT; EQUIPMENT; NUCLEAR FACILITIES; POWER PLANTS; REACTORS; TESTING; THERMAL POWER PLANTS; WATER COOLED REACTORS; WATER MODERATED REACTORS 210100*
-- Power Reactors, Nonbreeding, Light-Water Moderated, Boiling Water Cooled; 210200
-- Power Reactors, Nonbreeding, Light-Water Moderated, Nonboiling Water Cooled
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2015 Jun 28;17(24):15963-75. doi: 10.859e. Epub
2015 Jun 1.Effects of electronic structure on the hydration of PbNO3(+) and SrNO3(+) ion pairs.1, , .1Department of Chemistry, University of California, Berkeley, California , USA. erw@berkeley.edu.AbstractHydration of PbNO3(+) and SrNO3(+) with up to 30 water molecules was investigated with infrared photodissociation (IRPD) spectroscopy and with theory. These ions are the same size, yet the IRPD spectra of these ion pairs for n = 2-8 are significantly different. Bands in the bonded O-H region (~ cm(-1)) indicate that the onset of a second hydration shell begins at n = 5 for PbNO3(+) and n = 6 for SrNO3(+). Spectra for [PbNO3](+)(H2O)2-5 and [SrNO3](+)(H2O)3-6 indicate that the structures of clusters with Pb(ii) are hemidirected with a void in the coordinate sphere. A natural bond orbital analysis of [PbNO3](+)(H2O)5 indicates that the anisotropic solvation of the ion is due to a region of asymmetric electron density on Pb(ii) that can be explained by charge transfer from the nitrate and water ligands into unoccupied p-orbitals on Pb(ii). There are differences in the IRPD spectra of PbNO3(+) and SrNO3(+) with up to 25 water molecules attached. IR intensity in the bonded O-H region is blue-shifted by ~50 cm(-1) in nanodrops containing SrNO3(+) compared to those containing PbNO3(+), indicative of a greater perturbation of the water H-bond network by strontium. The free O-H stretches of surface water molecules in nanodrops containing 10, 15, 20, and 25 water molecules are red-shifted by ~3-8 cm(-1) for PbNO3(+) compared to those for SrNO3(+), consistent with more charge transfer between water molecules and Pb(ii). These results demonstrate that the different electronic structure of these ions significantly influences how they are solvated. PMID:
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External link. Please review our .乌灵胶囊治疗焦虑障碍44例临床观察--《中医药导报》2015年07期
乌灵胶囊治疗焦虑障碍44例临床观察
【摘要】：目的:观察乌灵胶囊治疗焦虑障碍的临床疗效。方法:将88例焦虑障碍患者随机分为对照组和治疗组。对照组44例予盐酸帕罗西汀片治疗,治疗组44例予盐酸帕罗西汀片及乌灵胶囊治疗;1个月后复诊,观察并记录两组患者治疗前后血脂中总胆固醇(TC)及汉密尔顿焦虑量表(HAMD)评分的变化,并评价临床疗效。结果:治疗后,治疗组TC、HAMD评分均低于对照组,差异有统计学意义(P0.05)。对照组和治疗组总有效率分别为79.5%、93.1%,两组比较,差异有统计学意义(P0.05)。结论:乌灵胶囊治疗焦虑障碍患者,能有效提高患者的临床疗效,改善患者血脂情况。
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据相关文献记载,我国焦虑障碍的年患病率为2.4%~3.2%[1]。该类患者在临床上主要表现明显的躯体症状、严重睡眠障碍,对患者的工作、学习等均会产生严重的不良影响,制约着患者的正常交往或生活能力[2]。单纯运用西药治疗,其临床效果不甚理想。本院在西药治疗的基础上,采用乌灵胶
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京公网安备75号Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.
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):132-6. doi: 10.1038/ng.510. Epub
2010 Jan 10.Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.1, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , .1Institute of Cancer Research, Sutton, Surrey, UK.AbstractTo identify new risk variants for chronic lymphocytic leukemia (CLL), we conducted a genome-wide association study of 299,983 tagging SNPs, with validation in four additional series totaling 2,503 cases and 5,789 controls. We identified four new risk loci for CLL at 2q37.3 (rs757978, FARP2; odds ratio (OR) = 1.39; P = 2.11 x 10(-9)), 8q24.21 (rs2456449; OR = 1.26; P = 7.84 x 10(-10)), 15q21.3 (rs7169431; OR = 1.36; P = 4.74 x 10(-7)) and 16q24.1 (rs305061; OR = 1.22; P = 3.60 x 10(-7)). We also found evidence for risk loci at 15q25.2 (rs783540, CPEB1; OR = 1.18; P = 3.67 x 10(-6)) and 18q21.1 (rs1036935; OR = 1.22; P = 2.28 x 10(-6)). These data provide further evidence for genetic susceptibility to this B-cell hematological malignancy.PMID:
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External link. Please review our .CNTNAP2 polymorphisms and structural brain connectivity: a diffusion-tensor imaging study.
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):1349-56. doi: 10.1016/j.jpsychires.. Epub
2013 Jul 17.CNTNAP2 polymorphisms and structural brain connectivity: a diffusion-tensor imaging study.1, , , , , , , , , , , , , , , .1Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02215, USA. clemm@bwh.harvard.eduAbstractCNTNAP2 is a gene on chromosome 7 that has shown associations with autism and schizophrenia, and there is evidence that it plays an important role for neuronal synchronization and brain connectivity. In this study, we assessed the relationship between Diffusion Tensor Imaging (DTI), a putative marker of anatomical brain connectivity, and multiple single nucleotide polymorphisms (SNPs) spread out over this large gene. 81 healthy controls and 44 patients with schizophrenia (all Caucasian) underwent DTI and genotyping of 31 SNPs within CNTNAP2. We employed Tract-based Spatial Statistics (TBSS) for inter-subject brain registration and computed average diffusivity values for six major white matter tracts. Analyses of Covariance (ANCOVAs) were computed to test for possible associations with genotypes. The strongest association, which survived rigorous Bonferroni correction, was between rs2710126 genotype and Fractional Anisotropy (FA) in the uncinate fasciculus (p = .00003). This anatomical location is particularly interesting given the enriched fronto-temporal expression of CNTNAP2 in the developing brain. For this SNP, no phenotype association has been reported before. There were several further genotype-DTI associations that were nominally significant but did not survive Bonferroni correction, including an association between axial diffusivity in the dorsal cingulum bundle and a region in intron 13 (represented by rs2710102, rs759178, rs2538991), which has previously been reported to be associated with anterior-posterior functional connectivity. We present new evidence about the effects of CNTNAP2 on brain connectivity, whose disruption has been hypothesized to be central to schizophrenia pathophysiology.(C) 2013 Published by Elsevier Ltd.KEYWORDS: A Caspr2; E G Magnet SchizophreniaPMID:
[PubMed - indexed for MEDLINE] Regions of interest based on the TBSS white matter skeleton and Johns Hopkins University (JHU) ICBMDTI-81 White-Matter Labels Atlas (; ).Six major white matter tracts were chosen for analysis: cingulum bundle, cingulate gyrus part (CB, turquoise), corpus callosum (CC, blue), superior longitudinal fasciculus (SLF, pink), anterior thalamic radiation (ATR, this comprised the JHU atlas labels “anterior limb of internal capsule” and “anterior corona radiata”), sagittal stratum (SS, according to the JHU atlas, this mainly comprises fibers of the inferior fronto-occipital and inferior longitudinal fasciculi), and uncinate fasciculus (UF, yellow). Coronal slices at MNI coordinates Y=-23, -2 and 7 are shown, following the radiological convention (right hemisphere is left on figure).J Psychiatr Res. ;47(10):.rs2710126 genotype groups differ in Fractional Anisotropy in the uncinate fasciculus. This genotype effect appears recessive, i.e., only homozygotes of the presumed risk allele (A) have lower Fractional Anisotropy. Error bars indicate 95% confidence intervalsJ Psychiatr Res. ;47(10):.Publication TypesMeSH TermsSubstancesGrant SupportFull Text SourcesMedical
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